Acta Crystallographica Section E (Feb 2010)

1,2-Dihydroxy-2-(3-methylbut-2-enyl)-3-oxo-2,3-dihydro-1H-indene-1-carboxylic acid monohydrate

  • Acácio Ivo Franscisco,
  • Gleiciani de Q. Silveira,
  • Jackson A. L. C. Resende,
  • Tatiane L. Balliano,
  • Valéria R. S. Malta,
  • Antonio Ventura Pinto

DOI
https://doi.org/10.1107/S1600536810000516
Journal volume & issue
Vol. 66, no. 2
pp. o341 – o341

Abstract

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The title compound, C15H16O5·H2O, is an intermediate of the Hooker oxidation reaction, used for the synthesis of 2-hydroxy-3-(2-methylprop-1-enyl)naphthalene-1,4-dione (nor-lapachol). The packing in the crystal structure is arranged by an O—H...O hydrogen-bonded network along the [100] and [010] directions. Each organic molecule is linked to four other molecules via the hydroxy groups. The water solvent molecule is connected to carboxylic acid groups by three hydrogen bonds.