Revista do Instituto de Medicina Tropical de São Paulo (Dec 1994)

Bacterial agents isolated from cerebrospinal fluid of patients with Acquired Immunodeficiency Syndrome (AIDS) and neurological complications Agentes bacterianos isolados de líquido cefalorraquidiano de pacientes com Síndrome de Imunodeficiência Adquirida (SIDA) e complicações neurológicas

  • Ilka Maria Landgraf,
  • Moisés Palaci,
  • Maria de Fátima Paiva Vieira,
  • Sueli Yoko Mizuka Ueki,
  • Maria Conceição Martins,
  • Daisy Nakamura Sato,
  • Lucilaine Ferrazoli,
  • Maria Alice Silva Telles,
  • Maria Cecília Outeiro Gorla,
  • Tania Mara Ibelli Vaz,
  • Rosemarie Lorenço,
  • Lilian Regina Macelloni Marques

DOI
https://doi.org/10.1590/S0036-46651994000600003
Journal volume & issue
Vol. 36, no. 6
pp. 491 – 496

Abstract

Read online

Cerebrospinal fluid (CSF) samples from 2083 patients with acquired immunodeficiency syndrome (AIDS) and neurological complications were bacteriologically examined during a period of 7 years (1984-1990). The percentage of patients who had at least one bacterial agent cultured from the CSF was 6.2%. Mycobacterium tuberculosis was the most frequently isolated agent (4.3%), followed by Mycobacterium avium complex or MAC (0.7%), Pseudomonas spp (0.5%), Enterobacter spp (0.4%), and Staphylococcus aureus (0.3%). Among 130 culture positive patients, 89 (68.5%) had M. tuberculosis and 15 (11.6%) had MAC. The frequency of bacterial isolations increased from 1988 (5.2%) to 1990 (7.2%), partly due to the increase in MAC isolations. Bacterial agents were more frequently isolated from patients in the age group 21-30 years and from women (pAmostras de líquido cefalorraquidiano (LCR) de 2083 pacientes com Síndrome de Imunodeficiência Adquirida (SIDA) e complicações neurológicas foram examinados durante um período de 7 anos (1984-1990). A porcentagem de pacientes que tiveram pelo menos um agente bacteriano cultivado do LCR foi de 6,2%. Mycobacterium tuberculosis foi o mais frequentemente isolado (4,3%), seguido do complexo Mycobacterium avium ou MAC (0,7%), de Pseudomonas spp (0,5%), Enterobacter spp (0,4%), e Staphylococcus aureus (0,3%). Entre 130 pacientes com cultura positiva, de 89 (68,5%) foi isolado M. tuberculosis e de 15 (11,6%) MAC. A frequência de isolamentos bacterianos aumentou de 1988 (5,2%) a 1990 (7,2%), particularmente devido ao maior isolamento de MAC. Os agentes bacterianos foram mais frequentemente isolados de pacientes na faixa etária de 21-30 anos e de mulheres (p<0.05).

Keywords