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ACS Central Science
(Jul 2018)
Immunomodulation of the NLRP3 Inflammasome through Structure-Based Activator Design and Functional Regulation via Lysosomal Rupture
Saikat Manna,
William J. Howitz,
Nathan J. Oldenhuis,
Alexander C. Eldredge,
Jingjing Shen,
Fnu Naorem Nihesh,
Melissa B. Lodoen,
Zhibin Guan,
Aaron P. Esser-Kahn
Affiliations
Saikat Manna
Department of Chemistry, University of California, Irvine, Irvine, California, United States
William J. Howitz
Department of Chemistry, University of California, Irvine, Irvine, California, United States
Nathan J. Oldenhuis
Department of Chemistry, University of California, Irvine, Irvine, California, United States
Alexander C. Eldredge
Department of Chemistry, University of California, Irvine, Irvine, California, United States
Jingjing Shen
Institute for Molecular Engineering, University of Chicago, Chicago, Illinois, United States
Fnu Naorem Nihesh
Department of Chemistry, University of California, Irvine, Irvine, California, United States
Melissa B. Lodoen
The Institute for Immunology, University of California, Irvine, Irvine, California, United States
Zhibin Guan
Department of Chemistry, University of California, Irvine, Irvine, California, United States
Aaron P. Esser-Kahn
Department of Chemistry, University of California, Irvine, Irvine, California, United States
DOI
https://doi.org/10.1021/acscentsci.8b00218
Journal volume & issue
Vol. 4, no. 8
pp. 982 – 995
Abstract
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No abstracts available.
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