Multiple conformations of trimeric spikes visualized on a non-enveloped virus

Yinong Zhang; Yanxiang Cui; Jingchen Sun; Z. Hong Zhou

doi:10.1038/s41467-022-28114-0

Nature Communications (Jan 2022)

Multiple conformations of trimeric spikes visualized on a non-enveloped virus

Yinong Zhang,
Yanxiang Cui,
Jingchen Sun,
Z. Hong Zhou

Affiliations

Yinong Zhang: Subtropical Sericulture and Mulberry Resources Protection and Safety Engineering Research Center, Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou
Yanxiang Cui: California Nanosystems Institute, University of California, Los Angeles (UCLA)
Jingchen Sun: Subtropical Sericulture and Mulberry Resources Protection and Safety Engineering Research Center, Guangdong Provincial Key Laboratory of Agro-animal Genomics and Molecular Breeding, College of Animal Science, South China Agricultural University, Guangzhou
Z. Hong Zhou: California Nanosystems Institute, University of California, Los Angeles (UCLA)

DOI: https://doi.org/10.1038/s41467-022-28114-0
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 9

Abstract

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Zhang and Cui et al. present in situ cryoEM structures of the trimeric spike of cytoplasmic polyhedrosis virus in both open and close conformations, and demonstrate that spike detachment from the capsid is triggered by the presence of SAM and ATP.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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