G3: Genes, Genomes, Genetics (Mar 2021)

A case of convergent-gene interference in the budding yeast knockout library causing chromosome instability

  • Molly R Gordon,
  • Jin Zhu,
  • Victoria Qu,
  • Rong Li

DOI
https://doi.org/10.1093/g3journal/jkab084
Journal volume & issue
Vol. 11, no. 5

Abstract

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AbstractTo maintain genome stability, organisms depend on faithful chromosome segregation, a process affected by diverse genetic pathways, some of which are not directly linked to mitosis. In this study, we set out to explore one such pathway represented by an undercharacterized gene, SNO1sno1ΔCTF13CTF13