Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (<i>Thymus serpyllum</i> L.) Herbal Dust—Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques

Živan Mrkonjić; Muammer Kaplan; Sanja Milošević; Danica Božović; Aleksandra Sknepnek; Dunja Miletić; Ivana Lazarević Mrkonjić; Dušan Rakić; Zoran Zeković; Branimir Pavlić

doi:10.3390/plants13060897

Plants (Mar 2024)

Green Extraction Approach for Isolation of Bioactive Compounds in Wild Thyme (<i>Thymus serpyllum</i> L.) Herbal Dust—Chemical Profile, Antioxidant and Antimicrobial Activity and Comparison with Conventional Techniques

Živan Mrkonjić,
Muammer Kaplan,
Sanja Milošević,
Danica Božović,
Aleksandra Sknepnek,
Dunja Miletić,
Ivana Lazarević Mrkonjić,
Dušan Rakić,
Zoran Zeković,
Branimir Pavlić

Affiliations

Živan Mrkonjić: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Muammer Kaplan: TUBITAK Marmara Research Centre, Institute of Chemical Technology, P.O. Box 21, 41470 Gebze, Kocaeli, Turkey
Sanja Milošević: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Danica Božović: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Aleksandra Sknepnek: Faculty of Agriculture, Institute of Food Technology and Biochemistry, University of Belgrade, 11000 Belgrade, Serbia
Dunja Miletić: Faculty of Agriculture, Institute of Food Technology and Biochemistry, University of Belgrade, 11000 Belgrade, Serbia
Ivana Lazarević Mrkonjić: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Dušan Rakić: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Zoran Zeković: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia
Branimir Pavlić: Faculty of Technology, University of Novi Sad, Bulevar Cara Lazara 1, 21000 Novi Sad, Serbia

DOI: https://doi.org/10.3390/plants13060897
Journal volume & issue: Vol. 13, no. 6
p. 897

Abstract

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The aim of this study was to provide a chemical profile and determine the antioxidant and antimicrobial activity of the essential oil (EO) and lipid extracts of Thymus serpyllum L. herbal dust obtained via conventional (hydrodistillation (HD) and Soxhlet extraction (SOX)) and novel extraction techniques (supercritical fluid extraction (SFE)). In addition, a comparative analysis of the chemical profiles of the obtained EO and extracts was carried out, as well as the determination of antioxidant, antibacterial and antifungal activity of the lipid extracts. According to the aforementioned antioxidant and antimicrobial activities and the monoterpene yield and selectivity, SFE provided significant advantages compared to the traditional techniques. In addition, SFE extracts could be considered to have great potential in terms of their utilization in the pharmaceutical and cosmetic industries, as well as appropriate replacements for synthetic additives in the food industry.

Published in Plants

ISSN: 2223-7747 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Botany
Website: http://www.mdpi.com/journal/plants

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