Nature Communications (Jul 2021)

GapClust is a light-weight approach distinguishing rare cells from voluminous single cell expression profiles

  • Botao Fa,
  • Ting Wei,
  • Yuan Zhou,
  • Luke Johnston,
  • Xin Yuan,
  • Yanran Ma,
  • Yue Zhang,
  • Zhangsheng Yu

DOI
https://doi.org/10.1038/s41467-021-24489-8
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 11

Abstract

Read online

While rare cell type identification is indispensable in single cell studies, powerful tools with high detection accuracy and computational efficiency are still lacking. Here, the authors propose a light-weight algorithm which can distinguish rare cell types from voluminous single cell expression profiles.