Nature Communications (Oct 2016)

Microtubule organization is determined by the shape of epithelial cells

  • Juan Manuel Gomez,
  • Lyubov Chumakova,
  • Natalia A. Bulgakova,
  • Nicholas H. Brown

DOI
https://doi.org/10.1038/ncomms13172
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 13

Abstract

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Interphase microtubule organization creates a structural scaffold for cargo delivery determining cell polarity and cell shape. Here the authors show that in Drosophilaepithelia the orientation of microtubules responds to cell shape, rather than the converse, and develop a simple model to mimic this behaviour.