Non-Invasive Prenatal Testing With Personal Reasons and Ethical Evaluation

Abstract

INTRODUCTION[|]Diagnosis of fetal anomaly, genetic disorders and some other fetal pathologies during prenatal period by using ultrasound, Doppler and genetic tests is called prenatal diagnosis. [¤]METHODS[|]The reason for prenatal screening is to detect serious fetal pathology and termination of these pregnancies with the consent of the family or to manage the pregnancy and delivery in the most appropriate way if the family do not agree with pregnancy termination.[¤]RESULTS[|] If high chromosomal anomaly risk is detected, this result should be confirmed by invasive procedures such as chorionic villus sampling (CVS) and amniocentesis. [¤]DISCUSSION AND CONCLUSION[|]Invasive procedures have some risks, most notably pregnancy loss. These problems of invasive procedures have led to pursuit of non-invasive test with high reliability and resulted with the development of Non-Invasive prenatal Testing (NIPT). NIPT is a new genetic method which is performed by using free fetal DNA (cffDNA, cell-free fetal DNA) obtained from the plasma of the pregnant woman. In this study, the ethical aspects of NIPT for personal reasons are discussed.[¤]

Keywords

• fetus
• ethics
• genetic testing
• prenatal diagnosis
• non-invasive prenatal testing
• free fetal dna testing