Infection and Drug Resistance (Jun 2022)
Bacterial Vaginosis and Associated Factors Among Pregnant Women Attending Antenatal Care in Harar City, Eastern Ethiopia
Abstract
Mohammed Ahmed, Desalegn Admassu, Degu Abate Department of Medical Laboratory Science, College of Health and Medical Sciences, Haramaya University, Harar, EthiopiaCorrespondence: Mohammed Ahmed Aliyi, Department of Medical Laboratory Science, College of Health and Medical Sciences, Haramaya University, P.O. Box 235, Harar, Ethiopia, Tel +251-921-658-970, Email [email protected]: Bacterial vaginosis is one of the most common causes of abnormal vaginal discharge in women of reproductive age, especially pregnant women. It is characterized by the decrement of lactobacilli and increasing proliferation of diverse anaerobic bacteria. The prevalence of bacterial vaginosis and contributing factors vary between countries, within the same country, and among different populations.Objective: The purpose of this study was to determine the prevalence of bacterial vaginosis and associated factors among pregnant women attending antenatal care from May 5–July 15, 2021 in health-care facilities found in Harar town, eastern Ethiopia.Methods and Materials: An institutional-based cross-sectional study was conducted among 248 pregnant women attending antenatal care through systematic random sampling. Data were collected using a structured questionnaire and two vaginal swabs were collected using sterile swabs and transported to the microbiology laboratory. Samples were analyzed using Amsel’s criteria or using Nugent scoring criteria and culture. Data were entered into EpiData version 3.1 and transferred to SPSS version 25 for analysis. Binary logistic regression was used to identify variables associated with bacterial vaginosis. P-value < 0.05 was considered statistically significant.Results: Altogether 248 pregnant women were included in the study. Overall, 21.4% (95% CI: 16, 27) of study participants had bacterial vaginosis. History of sexually transmitted infection (AOR = 6.0, 95% CI: 1.94, 19.07; P = 0.002), history of spontaneous abortion (AOR = 5.8, 95% CI: 1.55, 22.02; P = 0.009), multiple sex partners (AOR = 8.6, 95% CI: 2.93, 25.79; P = 0.000) and having vaginal discharge (AOR = 5.5, 95% CI: 2.48, 12.41; P = 0.000) were significantly associated with bacterial vaginosis.Conclusion: The prevalence of bacterial vaginosis is higher among symptomatic pregnant women and associated with a history of sexually transmitted infection, vaginal discharge, multiple sexual partners and spontaneous abortion.Keywords: bacterial vaginosis, lactobacilli, G. vaginalis, Amsel’s criteria, Nugent scoring system
