G3: Genes, Genomes, Genetics (May 2021)

Stability of DNA methylation and chromatin accessibility in structurally diverse maize genomes

  • Jaclyn M Noshay,
  • Zhikai Liang,
  • Peng Zhou,
  • Peter A Crisp,
  • Alexandre P Marand,
  • Candice N Hirsch,
  • Robert J Schmitz,
  • Nathan M Springer

DOI
https://doi.org/10.1093/g3journal/jkab190
Journal volume & issue
Vol. 11, no. 8

Abstract

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AbstractAccessible chromatin and unmethylated DNA are associated with many genes and cis-regulatory elements. Attempts to understand natural variation for accessible chromatin regions (ACRs) and unmethylated regions (UMRs) often rely upon alignments to a single reference genome. This limits the ability to assess regions that are absent in the reference genome assembly and monitor how nearby structural variants influence variation in chromatin state. In this study, de novo