Brain Sciences (Sep 2022)

Sixteen-Year Follow-Up in a Cavernous Sinus Hemangiopericytoma: Improved Outcomes over Radiotherapy Advances

  • Beatrice Detti,
  • Lilia Bardoscia,
  • Antonio Rosario Pisani,
  • Salvatore Cozzi,
  • Manuele Roghi,
  • Paolo Mammucci,
  • Angela Sardaro

DOI
https://doi.org/10.3390/brainsci12091209
Journal volume & issue
Vol. 12, no. 9
p. 1209

Abstract

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Intracranial hemangiopericytomas are rare tumors, accounting for 1% of all central nervous system malignancies. This tumor is considered at high risk of local and also distant metastases. Surgical excision is the gold standard for treatment, but it is seldom curative by itself. Adjuvant radiotherapy is often recommended. We report an overview and update of the available literature on one such rare but aggressive mesenchymal tumor, using the case of a 46-year-old woman affected by hemangiopericytoma of the cavernous sinus surgically removed and treated with adjuvant radiotherapy at our institution. After seven years, the patient underwent a local recurrence and was treated with exeresis and Gamma Knife radiotherapy. Sixteen years after the initial diagnosis, she is still well with stable disease.

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