Nature Communications (Apr 2022)

Transient viral exposure drives functionally-coordinated humoral immune responses in HIV-1 post-treatment controllers

  • Luis M. Molinos-Albert,
  • Valérie Lorin,
  • Valérie Monceaux,
  • Sylvie Orr,
  • Asma Essat,
  • Jérémy Dufloo,
  • Olivier Schwartz,
  • Christine Rouzioux,
  • Laurence Meyer,
  • Laurent Hocqueloux,
  • Asier Sáez-Cirión,
  • Hugo Mouquet,
  • ANRS VISCONTI Study Group

DOI
https://doi.org/10.1038/s41467-022-29511-1
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 17

Abstract

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A rare sub-population of people living with HIV-1 experience long-lasting viral remission after interrupting antiretroviral therapy and are considered post-treatment controllers. Here the authors characterise the humoral immune response to HIV-1 in a cohort of post-treatment controllers.