MODULATION OF BRAIN CONNECTIVITY, STRUCTURE, NEURON AND GLIA, AND MOTOR FUNCTION BY SAFINAMIDE MULTIMODAL ACTIONS IN A PRE-CLINICAL MODEL OF PARKINSON’S DISEASE

• Bruna Araújo,
• Jonas Campos,
• Rita Caridade-Silva,
• Bárbara Mendes-Pinheiro,
• Raquel Marques,
• Sandra Barata,
• Rui Lima,
• Joana Martins-Macedo,
• Eduardo Gomes,
• Benoit Larrat,
• António Salgado,
• Sébastien Mériaux,
• Sofia Domingues,
• Fábio Teixeira

Affiliations

Bruna Araújo

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; Institute for Research and Innovation in Health, Neurobiology And Neurologic Disorders, Porto, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal; Center for Translational Health and Medical Biotechnology Research, School Of Health, Polytechnic, University Of Porto, Porto, Portugal

Jonas Campos

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Rita Caridade-Silva

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; Institute for Research and Innovation in Health, Neurobiology And Neurologic Disorders, Porto, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal; Center for Translational Health and Medical Biotechnology Research, School Of Health, Polytechnic, University Of Porto, Porto, Portugal

Bárbara Mendes-Pinheiro

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Raquel Marques

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Sandra Barata

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Rui Lima

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Joana Martins-Macedo

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; Institute for Research and Innovation in Health, Neurobiology And Neurologic Disorders, Porto, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal; Center for Translational Health and Medical Biotechnology Research, School Of Health, Polytechnic, University Of Porto, Porto, Portugal

Eduardo Gomes

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; Institute for Research and Innovation in Health, Neurobiology And Neurologic Disorders, Porto, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal; Center for Translational Health and Medical Biotechnology Research, School Of Health, Polytechnic, University Of Porto, Porto, Portugal

Benoit Larrat

NeuroSpin, Université Paris-Saclay, Cea, Paris, France

António Salgado

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Sébastien Mériaux

NeuroSpin, Université Paris-Saclay, Cea, Paris, France

Sofia Domingues

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal

Fábio Teixeira

Life and Health Sciences Research Institute (ICVS), School Of Medicine, Braga, Portugal; Institute for Research and Innovation in Health, Neurobiology And Neurologic Disorders, Porto, Portugal; ICVS/3B’s Associate Lab, Pt Government Associated Lab, Guimarães, Portugal; Center for Translational Health and Medical Biotechnology Research, School Of Health, Polytechnic, University Of Porto, Porto, Portugal