The Principles of Antibody Therapy for Infectious Diseases with Relevance for COVID-19

Arturo Casadevall; Liise-anne Pirofski; Michael J. Joyner

doi:10.1128/mBio.03372-20

mBio (Apr 2021)

The Principles of Antibody Therapy for Infectious Diseases with Relevance for COVID-19

Arturo Casadevall,
Liise-anne Pirofski,
Michael J. Joyner

Affiliations

Arturo Casadevall: ORCiD; Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, USA
Liise-anne Pirofski: Department of Medicine, Division of Infectious Diseases, Albert Einstein College of Medicine, Bronx, New York, USA
Michael J. Joyner: Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, Rochester, Minnesota, USA

DOI: https://doi.org/10.1128/mBio.03372-20
Journal volume & issue: Vol. 12, no. 2

Abstract

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Antibody therapies such as convalescent plasma and monoclonal antibodies have emerged as major potential therapeutics for coronavirus disease 2019 (COVID-19). Immunoglobulins differ from conventional antimicrobial agents in that they mediate direct and indirect antimicrobial effects that work in concert with other components of the immune system.

Published in mBio

ISSN: 2161-2129 (Print); 2150-7511 (Online)
Publisher: American Society for Microbiology
Country of publisher: United States
LCC subjects: Science: Microbiology
Website: https://journals.asm.org/journal/mbio

About the journal