Severe Refractory Anaemia and Fever of Unknow Origin: Human Parvovirus B19 Reactivation

Abstract

Reactivation of human parvovirus B19 is exceptional and characteristic of immunosuppression, with anaemia being the predominant manifestation although pancytopenia and thrombotic microangiopathy may also occur. We describe a patient with a history of diffuse large B-cell lymphoma with pure erythrocyte aplasia due to reactivation of parvovirus B19, who was treated with corticosteroids and immunoglobulins.

Keywords

• human parvovirus b19
• pure red cell aplasia
• viral reactivation