Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature

Carmen Imma Aquino; Raffaele Tinelli; Alessandro Libretti; Riccardo Bertinato; Renzo Luciano Boldorini; Michele Giana; Felice Sorrentino; Luigi Nappi; Valentino Remorgida; Daniela Surico

doi:10.3390/medicina59081417

Medicina (Aug 2023)

Aggressive Pelvic Angiomyxoma in a Patient with Twin Pregnancy: Diagnosis, Treatment, and Clinical Complications in Light of the Literature

Carmen Imma Aquino,
Raffaele Tinelli,
Alessandro Libretti,
Riccardo Bertinato,
Renzo Luciano Boldorini,
Michele Giana,
Felice Sorrentino,
Luigi Nappi,
Valentino Remorgida,
Daniela Surico

Affiliations

Carmen Imma Aquino: Department of Gynecology and Obstetrics, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy
Raffaele Tinelli: Department of Obstetrics and Gynecology, “Valle D’Itria” Hospital, Martina Franca, 74015 Taranto, Italy
Alessandro Libretti: Department of Gynecology and Obstetrics, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy
Riccardo Bertinato: Department of Gynecology and Obstetrics, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy
Renzo Luciano Boldorini: Department of Pathology, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy
Michele Giana: Department of Gynecology and Obstetrics, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy
Felice Sorrentino: Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, 71121 Foggia, Italy
Luigi Nappi: Department of Medical and Surgical Sciences, Institute of Obstetrics and Gynecology, University of Foggia, 71121 Foggia, Italy
Valentino Remorgida: Department of Gynecology and Obstetrics, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy
Daniela Surico: Department of Gynecology and Obstetrics, “Maggiore della Carità” Hospital, University of Piemonte Orientale, 28100 Novara, Italy

DOI: https://doi.org/10.3390/medicina59081417
Journal volume & issue: Vol. 59, no. 8
p. 1417

Abstract

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(1) Background: Aggressive angiomyxoma is a mesenchymal cancer that is rare during pregnancy. It is a neoplasm that relapses and infiltrates the nearest structures. Our aim is to evaluate the management and outcomes of an observed case, in light of the current literature. (2) Methods: We observed this condition at the “Maggiore della Carità” Hospital in Novara (Italy) in a patient with an initial twin pregnancy and a suspected pelvic mass. The words “angiomyxoma” and “pregnancy” were searched on the main online scientific search sources (PubMed, Google Scholar, Scopus, WES, and Embase, etc.). (3) Results: The patient underwent surgery with a complicated follow-up, but recent negative controls. We analyzed the literature about the topic and found only 24 similar clinical cases. (4) Conclusions: Considering the current literature, it is useful to assess an aggressive angiomyxoma in the differential diagnosis of soft masses in pregnant women. The treatment of choice is surgical excision, and vaginal delivery is feasible. The therapeutic decision depends on each case.

Published in Medicina

ISSN: 1010-660X (Print); 1648-9144 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine: Medicine (General)
Website: https://www.mdpi.com/journal/medicina

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