VIKOR Method for Diabetic Nephropathy Risk Factors Analysis

Abstract

Diabetic kidney disease is an important complication of type 2 diabetes mellitus (T2DM) and has an economic impact in growth due to the increasing prevalence of T2DM. Identification of diabetic kidney disease risk factors is a priority for both the patient and the healthcare system. The aim of our study was to rank the risk factors using VIKOR method applied on a database with patients with T2DM. Data from 53 T2DM patients were analyzed with VIKOR method. 18 possible risk factors were taken in consideration as alternatives and four separate criteria of renal function: two for albumin excretion – quantified as urinary albumin/creatinine ratio (UACR) and two for GFR (glomerular filtration rate). In the top of the VIKOR method hierarchy was serum adiponectin followed by triglycerides, systolic blood pressure, duration of diabetes and age. Malondialdehyde and HDL-cholesterol influenced chronic kidney disease as protective factors (18th, respective 17th position in the hierarchy). VIKOR method brought new information about the similarity between the positions of some factors in the hierarchy.

Keywords

• Attribute relevance analysis
• VIKOR method
• Type 2 diabetes mellitus
• Chronic kidney disease
• Oxidative stress