"Golden Era of Antibiotics" - Coming to an end !!!

Abstract

Resistance to antibiotics is increasing at an alarming rate. This is due to superbugs, producing heterogenous groups of enzymes, β-lactamases which inactivate β-lactam antibiotics and others as well. The β-lactamase Carbapenemase, has become a threat to the Carbapenems, which were the last resort β-lactam antibiotics. This article is a highlight on β- lactamases, specially Carbapenemases which includes New Delhi Metallo- β-lactamase - NDM-1.

Keywords

• β - lactamantibiotics
• β - lactamases
• carbapenemase
• superbugs