Chromosome Aberrations Produced by Mestranol in Human Lymphocyte Cultures

Teodorović Radislava; Drašković Vladimir; Đurić Spomenka; Nenadović Kartarina; Mirilović Milorad; Janković Ljiljana

doi:10.2478/acve-2019-0036

Acta Veterinaria (Dec 2019)

Chromosome Aberrations Produced by Mestranol in Human Lymphocyte Cultures

Teodorović Radislava,
Drašković Vladimir,
Đurić Spomenka,
Nenadović Kartarina,
Mirilović Milorad,
Janković Ljiljana

Affiliations

Teodorović Radislava: Department of Animal Hygiene, Faculty of Veterinary Medicine, University of Belgrade, Bul. Oslobođenja 18 Belgrade, Serbia
Drašković Vladimir: Department of Animal Hygiene, Faculty of Veterinary Medicine, University of Belgrade, Bul. Oslobođenja 18 Belgrade, Serbia
Đurić Spomenka: Department of Economics and Statistics, Faculty of Veterinary Medicine, University of Belgrade, Bul. Oslobođenja 18 Belgrade, Serbia
Nenadović Kartarina: Department of Animal Hygiene, Faculty of Veterinary Medicine, University of Belgrade, Bul. Oslobođenja 18 Belgrade, Serbia
Mirilović Milorad: Department of Economics and Statistics, Faculty of Veterinary Medicine, University of Belgrade, Bul. Oslobođenja 18 Belgrade, Serbia
Janković Ljiljana: Department of Animal Hygiene, Faculty of Veterinary Medicine, University of Belgrade, Bul. Oslobođenja 18 Belgrade, Serbia

DOI: https://doi.org/10.2478/acve-2019-0036
Journal volume & issue: Vol. 69, no. 4
pp. 426 – 433

Abstract

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In this investigation, the genotoxic properties of mestranol were examined in vitro. Human lymphocyte cultures were exposed for 72 h to mestranol at concentrations of 7.5, 15 and 30 µg/g. The genotoxic effects of the chemosterilant were assessed by numerical and structural chromosome aberrations.

Published in Acta Veterinaria

ISSN: 1820-7448 (Online)
Publisher: Sciendo
Country of publisher: Serbia
LCC subjects: Agriculture: Animal culture: Veterinary medicine
Website: https://sciendo.com/journal/ACVE

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Abstract

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