Association of Obesity with Cardiovascular Diseases

Abstract

ABSTRACT Obesity is distinct as pro-inflammatory/ pro-oxidative state related with malfunctioning of adipose tissue. Impairment of the function of endocrine and paracrine systems results to disruption of homeostasis of endothelium and vascular system. This pathology along with atherosclerosis shows coronary heart disease and cerebrovascular problems. Obesity may be related to aging, diet, childhood and adulthood. It is also related with old age, sex steroids and may also be linked with metabolic impairments. Along with types of obesity, obesity paradox is also discussed. This narrative review covered an extensive literature search on PubMed, Google Scholar and Medline for papers on the impact and association of obesity with cardiovascular diseases since December 2022. Keywords: Obesity, Cardiovascular disease, Obesity paradox.