National Journal of Laboratory Medicine (Jan 2015)
Extended Spectrum Beta Lactamase Producing Shigella Flexneri: A Therapeautic Concern?
Abstract
Shigella flexneri is the most commonly isolated species in the developing world. Prompt and appropriate therapy is necessary in shortening the duration of clinical symptoms, as well as to prevent transmission of infection to close contacts. Emerging multidrug resistant strain of Shigella is a growing concern across the globe and in India. Herein we report a case of dysentery in a child caused by an extended spectrum beta lactamase (ESBL) producing and multidrug resistant (MDR) S. flexeneri so as to alert the clinicians, microbiologists and epidemiologists regarding the emergence of resistance in Shigella spp. An outbreak of shigellosis by such resistant strains in overcrowded communities will be a tough challenge in the containment of the disease.
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