G3: Genes, Genomes, Genetics (May 2017)

TheCellMap.org: A Web-Accessible Database for Visualizing and Mining the Global Yeast Genetic Interaction Network

  • Matej Usaj,
  • Yizhao Tan,
  • Wen Wang,
  • Benjamin VanderSluis,
  • Albert Zou,
  • Chad L. Myers,
  • Michael Costanzo,
  • Brenda Andrews,
  • Charles Boone

DOI
https://doi.org/10.1534/g3.117.040220
Journal volume & issue
Vol. 7, no. 5
pp. 1539 – 1549

Abstract

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Providing access to quantitative genomic data is key to ensure large-scale data validation and promote new discoveries. TheCellMap.org serves as a central repository for storing and analyzing quantitative genetic interaction data produced by genome-scale Synthetic Genetic Array (SGA) experiments with the budding yeast Saccharomyces cerevisiae. In particular, TheCellMap.org allows users to easily access, visualize, explore, and functionally annotate genetic interactions, or to extract and reorganize subnetworks, using data-driven network layouts in an intuitive and interactive manner.

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