Molecules (Jan 2023)

Exploration of the Use of Natural Compounds in Combination with Chemotherapy Drugs for Tumor Treatment

  • Jianping Wu,
  • Yunheng Li,
  • Qiaojun He,
  • Xiaochun Yang

DOI
https://doi.org/10.3390/molecules28031022
Journal volume & issue
Vol. 28, no. 3
p. 1022

Abstract

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Currently, chemotherapy is the main treatment for tumors, but there are still problems such as unsatisfactory chemotherapy results, susceptibility to drug resistance, and serious adverse effects. Natural compounds have numerous pharmacological activities which are important sources of drug discovery for tumor treatment. The combination of chemotherapeutic drugs and natural compounds is gradually becoming an important strategy and development direction for tumor treatment. In this paper, we described the role of natural compounds in combination with chemotherapeutic drugs in synergizing, reducing drug resistance, mitigating adverse effects and related mechanisms, and providing new insights for future oncology research.

Keywords