Interpretation of “International Consensus Guidelines for Diagnosis and Treatment of Food Protein-Induced Enterocolitis Syndrome”

Abstract

Food protein-induced enterocolitis syndrome （FPIES） is a critical non-IgE-mediated food allergy,occurs mostly in infants. Dehydration shock may occur in severe FPIES cases upon acute onset, and growth retardation probably occurs in patients with chronic FPIES. In 2017, Adverse Reactions to Foods Committee, American College of Allergy, Asthma and Immunology and International FPIES Association jointly formulated and released International Consensus Guidelines for Diagnosis and Treatment of Food Protein-induced Enterocolitis Syndrome, which is the only diagnosis and treatment guidelines for FPIES. Based on literature review and clinical evidence, this guideline proposes 30 statements, which provide reference for clinical diagnosis and treatment of FPIES. At present, medical staff has a low awareness rate of FPIES, and relevant studies are still lacking in China. In this article, clinical manifestations, diagnosis, auxiliary examination, treatment and prognosis of FPIES were explicitly interpreted, aiming to deepen the understanding of FPIES and improve the diagnosis and treatment levels among Chinese medical staff.

Keywords

• |food protein-induced enterocolitis syndrome|guideline|diagnosis|treatment|prognosis