Postconditioning with D-limonene exerts neuroprotection in rats via enhancing mitochondrial activity

Zhang Leguo; Zhao Zeyu; Jia Jianpu; Zhang Liran; Xia Ruixue; Zhu Cuimin

doi:10.1515/tjb-2022-0290

Türk Biyokimya Dergisi (Oct 2023)

Postconditioning with D-limonene exerts neuroprotection in rats via enhancing mitochondrial activity

Zhang Leguo,
Zhao Zeyu,
Jia Jianpu,
Zhang Liran,
Xia Ruixue,
Zhu Cuimin

Affiliations

Zhang Leguo: The Eight Department of Neurology, Cangzhou Central Hospital, Cangzhou, Hebei Province, P.R. China
Zhao Zeyu: The Eight Department of Neurology, Cangzhou Central Hospital, Cangzhou, Hebei Province, P.R. China
Jia Jianpu: The Eight Department of Neurology, Cangzhou Central Hospital, Cangzhou, Hebei Province, P.R. China
Zhang Liran: The Eight Department of Neurology, Cangzhou Central Hospital, Cangzhou, Hebei Province, P.R. China
Xia Ruixue: The Eight Department of Neurology, Cangzhou Central Hospital, Cangzhou, Hebei Province, P.R. China
Zhu Cuimin: The Five Department of Pediatrics, Cangzhou Central Hospital, Cangzhou, Hebei Province, P.R. China

DOI: https://doi.org/10.1515/tjb-2022-0290
Journal volume & issue: Vol. 48, no. 6
pp. 682 – 689

Abstract

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The key component of neuroprotection after cerebral ischemia–reperfusion (I–R) injury is mitochondrial improvement. By focusing on the function of mitochondrial biogenesis and ATP-sensitive potassium (mK–ATP) channels and inflammatory responses, the current study assessed the neuroprotective potentials of lemon essential oil, D-limonene (LIM), in rats with cerebral I–R injury.

Published in Türk Biyokimya Dergisi

ISSN: 1303-829X (Online)
Publisher: De Gruyter
Country of publisher: Germany
LCC subjects: Science: Chemistry: Organic chemistry: Biochemistry
Website: https://www.degruyter.com/journal/key/tjb/html

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