Identification of a Novel Class of BRD4 Inhibitors by Computational Screening and Binding Simulations

• Bryce K. Allen,
• Saurabh Mehta,
• Stuart W. J. Ember,
• Jin-Yi Zhu,
• Ernst Schönbrunn,
• Nagi G. Ayad,
• Stephan C. Schürer

Affiliations

Bryce K. Allen

†Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States

Saurabh Mehta

†Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States

Stuart W. J. Ember

Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Jin-Yi Zhu

Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Ernst Schönbrunn

Drug Discovery Department, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

Nagi G. Ayad

⊥Center for Therapeutic Innovation Miller School of Medicine, University of Miami, Miami, Florida, United States

Stephan C. Schürer

†Department of Molecular and Cellular Pharmacology, Miller School of Medicine, University of Miami, Miami, Florida, United States