Tobacco Induced Diseases (Jun 2023)

Effect of smoking-related COVID-19 risk messaging on smoking cessation in community smokers: A pragmatic randomized controlled trial

  • Xue Weng<sup>*<sup/>,
  • Tzu Tsun Luk<sup>*<sup/>,
  • Yongda Socrates Wu,
  • Sheng Zhi Zhao,
  • Derek Yee Tak Cheung,
  • Henry Sau Chai Tong,
  • Vienna Wai Yin Lai,
  • Tai Hing Lam,
  • Man Ping Wang

DOI
https://doi.org/10.18332/tid/163176
Journal volume & issue
Vol. 21, no. June
pp. 1 – 11

Abstract

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Introduction Observational and experimental studies have suggested that messaging on smoking-related COVID-19 risk may promote smoking abstinence, but evidence from randomized clinical trials (RCTs) is lacking. Methods This was a pragmatic RCT in Hong Kong, China, to compare the effectiveness of communicating smoking-related COVID-19 risk with generic cessation support on abstinence. Both groups received brief cessation advice at baseline. The intervention group received messaging on smoking-related COVID-19 risk and cessation support via instant messaging for three months (16 messages in total), which highlighted the increased risk of severe COVID-19 and deaths, and potentially higher risk of viral exposure (e.g. due to mask removal) for smokers. The control group received generic text messaging support for three months (16 messages). The primary outcomes were biochemically validated 7-day point prevalence abstinence (PPA) at 3 and 6 months. Intention to treat analyses was used. Results Between 13 June and 30 October 2020, 1166 participants were randomly assigned to an intervention (n=583) or control (n=583) group. By intention-totreat, validated 7-day PPA did not significantly differ between the intervention and control groups at three months (9.6% and 11.8%, relative risk, RR=0.81; 95% CI: 0.58–1.13, p=0.22) or six months (9.3% and 11.7%, RR=0.79; 95% CI: 0.57–1.11, p=0.18). A higher perceived severity of COVID-19 in smokers at baseline was associated with a greater validated 7-day PPA at six months, and a marginally significant intervention effect on changes in perceived severity from baseline through 6 months was found (p for group × time interaction = 0.08). Conclusions Communicating smoking-related COVID-19 risk via instant messaging was not more effective in increasing smoking abstinence than generic cessation support. TRIAL REGISTRATION The study is registered on ClinicalTrials.gov Identifier: NCT04399967

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