A Hidden Markov Model reveals magnetoencephalography spectral frequency-specific abnormalities of brain state power and phase-coupling in neuropathic pain

Camille Fauchon; Junseok A. Kim; Rima El-Sayed; Natalie R. Osborne; Anton Rogachov; Joshua C. Cheng; Kasey S. Hemington; Rachael L. Bosma; Benjamin T. Dunkley; Jiwon Oh; Anuj Bhatia; Robert D. Inman; Karen Deborah Davis

doi:10.1038/s42003-022-03967-9

Communications Biology (Sep 2022)

A Hidden Markov Model reveals magnetoencephalography spectral frequency-specific abnormalities of brain state power and phase-coupling in neuropathic pain

Camille Fauchon,
Junseok A. Kim,
Rima El-Sayed,
Natalie R. Osborne,
Anton Rogachov,
Joshua C. Cheng,
Kasey S. Hemington,
Rachael L. Bosma,
Benjamin T. Dunkley,
Jiwon Oh,
Anuj Bhatia,
Robert D. Inman,
Karen Deborah Davis

Affiliations

Camille Fauchon: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Junseok A. Kim: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Rima El-Sayed: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Natalie R. Osborne: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Anton Rogachov: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Joshua C. Cheng: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Kasey S. Hemington: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Rachael L. Bosma: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Benjamin T. Dunkley: Neurosciences & Mental Health Program, The Hospital for Sick Children Research Institute
Jiwon Oh: Div of Neurology, Dept of Medicine, St. Michael’s Hospital
Anuj Bhatia: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network
Robert D. Inman: Institute of Medical Science, University of Toronto
Karen Deborah Davis: Division of Brain, Imaging, and Behaviour, Krembil Brain Institute, University Health Network

DOI: https://doi.org/10.1038/s42003-022-03967-9
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 12

Abstract

Read online

A comparative analysis on resting-state magnetoencephalography data from healthy controls and patients with chronic pain reveals spectral frequency-specific dysregulation and a temporal imbalance of brain microstates in chronic neuropathic pain.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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