A Multimethodological Characterization of <i>Cannabis sativa</i> L. Inflorescences from Seven Dioecious Cultivars Grown in Italy: The Effect of Different Harvesting Stages

Mattia Spano; Giacomo Di Matteo; Cinzia Ingallina; Bruno Botta; Deborah Quaglio; Francesca Ghirga; Silvia Balducci; Silvia Cammarone; Enio Campiglia; Anna Maria Giusti; Giuliana Vinci; Mattia Rapa; Salvatore Ciano; Luisa Mannina; Anatoly P. Sobolev

doi:10.3390/molecules26102912

Molecules (May 2021)

A Multimethodological Characterization of <i>Cannabis sativa</i> L. Inflorescences from Seven Dioecious Cultivars Grown in Italy: The Effect of Different Harvesting Stages

Mattia Spano,
Giacomo Di Matteo,
Cinzia Ingallina,
Bruno Botta,
Deborah Quaglio,
Francesca Ghirga,
Silvia Balducci,
Silvia Cammarone,
Enio Campiglia,
Anna Maria Giusti,
Giuliana Vinci,
Mattia Rapa,
Salvatore Ciano,
Luisa Mannina,
Anatoly P. Sobolev

Affiliations

Mattia Spano: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Giacomo Di Matteo: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Cinzia Ingallina: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Bruno Botta: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Deborah Quaglio: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Francesca Ghirga: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Silvia Balducci: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Silvia Cammarone: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Enio Campiglia: Department of Agricultural and Forest Sciences, University of Tuscia, Via San Camillo de Lellis snc, 01100 Viterbo, Italy
Anna Maria Giusti: Department of Experimental Medicine, Sapienza University of Rome, P.le Aldo Moro 5, 00185 Rome, Italy
Giuliana Vinci: Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy
Mattia Rapa: Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy
Salvatore Ciano: Department of Management, Sapienza University of Rome, Via del Castro Laurenziano 9, 00161 Rome, Italy
Luisa Mannina: Department of Chemistry and Technology of Drugs, Sapienza University of Rome, Piazzale Aldo Moro 5, 00185 Rome, Italy
Anatoly P. Sobolev: Institute for Biological Systems, Magnetic Resonance Laboratory “Segre-Capitani”, CNR, Via Salaria Km 29.300, 00015 Monterotondo, Italy

DOI: https://doi.org/10.3390/molecules26102912
Journal volume & issue: Vol. 26, no. 10
p. 2912

Abstract

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The chemical profile of the female inflorescence extracts from seven Cannabis sativa L. dioecious cultivars (Carmagnola, Fibranova, Eletta Campana, Antal, Tiborszallasi, Kompolti, and Tisza) was monitored at three harvesting stages (4, 14, and 30 September), reaching from the beginning of flowering to end of flowering/beginning of seed formation, using untargeted nuclear magnetic resonance (NMR) and targeted (ultra-high-performance liquid chromatography (UHPLC) and spectrophotometry) analyses. The tetrahydrocannabinol content was always below the legal limits (Cannabis sativa L. inflorescences of each analyzed dioecious hemp cultivar presented a peculiar chemical profile affected by the harvesting stage. This information could be useful for producers and industries to harvest inflorescences in the appropriate stage to obtain samples with a peculiar chemical profile suitable for proper applications.

Published in Molecules

ISSN: 1420-3049 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Organic chemistry
Website: http://www.mdpi.com/journal/molecules

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