Frontiers in Immunology (Dec 2023)
Simulating immunosuppressive mechanism of Microplitis bicoloratus bracovirus coordinately fights Spodoptera frugiperda
- Xing-Cheng Li,
- Xing-Cheng Li,
- Xing-Cheng Li,
- Yin-Chen Ma,
- Yin-Chen Ma,
- Yin-Chen Ma,
- Jin Long,
- Jin Long,
- Jin Long,
- Xiang Yan,
- Xiang Yan,
- Xiang Yan,
- Nan-Nan Peng,
- Nan-Nan Peng,
- Nan-Nan Peng,
- Cheng-Hui Cai,
- Cheng-Hui Cai,
- Cheng-Hui Cai,
- Wen-Feng Zhong,
- Wen-Feng Zhong,
- Wen-Feng Zhong,
- Yong-Biao Huang,
- Yong-Biao Huang,
- Yong-Biao Huang,
- Xin Qiao,
- Xin Qiao,
- Xin Qiao,
- Li-Xiang Zhou,
- Li-Xiang Zhou,
- Li-Xiang Zhou,
- Qiu-Chen Cai,
- Qiu-Chen Cai,
- Qiu-Chen Cai,
- Chang-Xu Cheng,
- Chang-Xu Cheng,
- Chang-Xu Cheng,
- Gui-Fang Zhou,
- Gui-Fang Zhou,
- Gui-Fang Zhou,
- Yun-Feng Han,
- Yun-Feng Han,
- Yun-Feng Han,
- Hong-Yu Liu,
- Hong-Yu Liu,
- Hong-Yu Liu,
- Qi Zhang,
- Qi Zhang,
- Qi Zhang,
- Hong-Mei Tang,
- Hong-Mei Tang,
- Hong-Mei Tang,
- Jiang-Hui Meng,
- Jiang-Hui Meng,
- Jiang-Hui Meng,
- Kai-Jun Luo,
- Kai-Jun Luo,
- Kai-Jun Luo
Affiliations
- Xing-Cheng Li
- School of Life Sciences, Yunnan University, Kunming, China
- Xing-Cheng Li
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Xing-Cheng Li
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Yin-Chen Ma
- School of Life Sciences, Yunnan University, Kunming, China
- Yin-Chen Ma
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Yin-Chen Ma
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Jin Long
- School of Life Sciences, Yunnan University, Kunming, China
- Jin Long
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Jin Long
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Xiang Yan
- School of Life Sciences, Yunnan University, Kunming, China
- Xiang Yan
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Xiang Yan
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Nan-Nan Peng
- School of Life Sciences, Yunnan University, Kunming, China
- Nan-Nan Peng
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Nan-Nan Peng
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Cheng-Hui Cai
- School of Life Sciences, Yunnan University, Kunming, China
- Cheng-Hui Cai
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Cheng-Hui Cai
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Wen-Feng Zhong
- School of Life Sciences, Yunnan University, Kunming, China
- Wen-Feng Zhong
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Wen-Feng Zhong
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Yong-Biao Huang
- School of Life Sciences, Yunnan University, Kunming, China
- Yong-Biao Huang
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Yong-Biao Huang
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Xin Qiao
- School of Life Sciences, Yunnan University, Kunming, China
- Xin Qiao
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Xin Qiao
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Li-Xiang Zhou
- School of Life Sciences, Yunnan University, Kunming, China
- Li-Xiang Zhou
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Li-Xiang Zhou
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Qiu-Chen Cai
- School of Life Sciences, Yunnan University, Kunming, China
- Qiu-Chen Cai
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Qiu-Chen Cai
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Chang-Xu Cheng
- School of Life Sciences, Yunnan University, Kunming, China
- Chang-Xu Cheng
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Chang-Xu Cheng
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Gui-Fang Zhou
- School of Life Sciences, Yunnan University, Kunming, China
- Gui-Fang Zhou
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Gui-Fang Zhou
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Yun-Feng Han
- School of Life Sciences, Yunnan University, Kunming, China
- Yun-Feng Han
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Yun-Feng Han
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Hong-Yu Liu
- School of Life Sciences, Yunnan University, Kunming, China
- Hong-Yu Liu
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Hong-Yu Liu
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Qi Zhang
- School of Life Sciences, Yunnan University, Kunming, China
- Qi Zhang
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Qi Zhang
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Hong-Mei Tang
- School of Life Sciences, Yunnan University, Kunming, China
- Hong-Mei Tang
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Hong-Mei Tang
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Jiang-Hui Meng
- School of Life Sciences, Yunnan University, Kunming, China
- Jiang-Hui Meng
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Jiang-Hui Meng
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- Kai-Jun Luo
- School of Life Sciences, Yunnan University, Kunming, China
- Kai-Jun Luo
- Yunnan International Joint Laboratory of Virology & Immunology, Yunnan University, Kunming, China
- Kai-Jun Luo
- Key Laboratory of the University in Yunnan Province for International Cooperation in Intercellular Communications and Regulations, Yunnan University, Kunming, China
- DOI
- https://doi.org/10.3389/fimmu.2023.1289477
- Journal volume & issue
-
Vol. 14
Abstract
Parasitoid wasps control pests via a precise attack leading to the death of the pest. However, parasitoid larvae exhibit self-protection strategies against bracovirus-induced reactive oxygen species impairment. This has a detrimental effect on pest control. Here, we report a strategy for simulating Microplitis bicoloratus bracovirus using Mix-T dsRNA targeting 14 genes associated with transcription, translation, cell–cell communication, and humoral signaling pathways in the host, and from wasp extracellular superoxide dismutases. We implemented either one-time feeding to the younger instar larvae or spraying once on the corn leaves, to effectively control the invading pest Spodoptera frugiperda. This highlights the conserved principle of “biological pest control,” as elucidated by the triple interaction of parasitoid-bracovirus-host in a cooperation strategy of bracovirus against its pest host.
Keywords
- bracovirus
- transcription signaling pathway
- translation signaling pathway
- cell-cell communication
- PGE2 pathway
- dsRNA
