Инновационная медицина Кубани (Sep 2019)

Lipofilling. The review of the technique. Modern opportunities and prospects for dermal scar correction

  • Yu. A. Sergeeva,
  • A. Kh. Kade,
  • S. B. Bogdanov,
  • A. I. Trofimenko

DOI
https://doi.org/10.35401/2500-0268-2019-15-3-62-67
Journal volume & issue
Vol. 0, no. 3
pp. 62 – 67

Abstract

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Since of the invention lipofilling, there was a significant change in ideas of the role used autologous fat tissue (Auto Fat) from natural filler of defects to the product for stimulating regeneration. There was a considerable evolution in technology of liposuction and Auto Fat processing, material and methodical providing of the procedure was improved. Opening and studying role of the stromal-vascular fraction (SVF) of the adipose tissue, in particular mesenchymal stem cells of the adipose tissue (MSC FT), promoted considerable extension of indications while using this method in aesthetic medicine. During experience accumulation of lipofilling application new concepts of application of Auto Fat in combination with MSC FT, platelet-enriched plasma (PRP) and growth factors were developed for scar correction. Understanding of a key role recipient area in succesful engrafting Auto Fat on scars resulted in development of transcutaneous aponeurotomy in a combination with a lipofilling (riggotomy). The procedure of a nanolipofilling which can be considered an attempt of the isolated use of lipofilling for regeneration stimulation and remodeling of cicatricial tissue was developed. However, despite the achieved success, carrying out further researches which would allow to confirm this method efficacy from the point of view evidence-based medicine and develop clear clinical guidelines about its application for treatment of dermal scars would be necessary.

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