Vaccines (Dec 2021)

Current Take on Systemic Sclerosis Patients’ Vaccination Recommendations

  • Giuseppe Murdaca,
  • Giovanni Noberasco,
  • Dario Olobardi,
  • Claudio Lunardi,
  • Matteo Maule,
  • Lorenzo Delfino,
  • Massimo Triggiani,
  • Chiara Cardamone,
  • Devis Benfaremo,
  • Gianluca Moroncini,
  • Angelo Vacca,
  • Nicola Susca,
  • Sebastiano Gangemi,
  • Paola Quattrocchi,
  • Laura Sticchi,
  • Giancarlo Icardi,
  • Andrea Orsi

DOI
https://doi.org/10.3390/vaccines9121426
Journal volume & issue
Vol. 9, no. 12
p. 1426

Abstract

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Systemic sclerosis (SSc) is a rare autoimmune inflammatory rheumatic disease. The prevalence of SSc ranges from 7 to 700 cases per million worldwide. Due to multiple organ involvement and constant inflammatory state, this group of patients presents an increased risk of infectious diseases. This paper aimed to gather the up-to-date evidence on vaccination strategies for patients with SSc and to be a useful tool for the prevention and management of infectious diseases. The authors conducted a scoping review in which each paragraph presents data on a specific vaccine’s safety, immunogenicity, and efficacy. The work deals with the following topics: SARS-CoV-2, seasonal influenza, S. pneumoniae, HAV, HBV, HZV, N. meningitidis, H. influenzae, HPV, and diphtheria-tetanus-pertussis.

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