Nature Communications (Jun 2020)
Ultrafast photochemistry produces superbright short-wave infrared dots for low-dose in vivo imaging
- Harrisson D. A. Santos,
- Irene Zabala Gutiérrez,
- Yingli Shen,
- José Lifante,
- Erving Ximendes,
- Marco Laurenti,
- Diego Méndez-González,
- Sonia Melle,
- Oscar G. Calderón,
- Enrique López Cabarcos,
- Nuria Fernández,
- Irene Chaves-Coira,
- Daniel Lucena-Agell,
- Luis Monge,
- Mark D. Mackenzie,
- José Marqués-Hueso,
- Callum M. S. Jones,
- Carlos Jacinto,
- Blanca del Rosal,
- Ajoy K. Kar,
- Jorge Rubio-Retama,
- Daniel Jaque
Affiliations
- Harrisson D. A. Santos
- Fluorescence Imaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid
- Irene Zabala Gutiérrez
- Departamento de Química en Ciencias Farmacéuticas, Universidad Complutense de Madrid
- Yingli Shen
- Fluorescence Imaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid
- José Lifante
- Nanobiology Group, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Ramón y Cajal
- Erving Ximendes
- Fluorescence Imaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid
- Marco Laurenti
- Departamento de Química en Ciencias Farmacéuticas, Universidad Complutense de Madrid
- Diego Méndez-González
- Departamento de Química en Ciencias Farmacéuticas, Universidad Complutense de Madrid
- Sonia Melle
- Department of Optics, Complutense University of Madrid
- Oscar G. Calderón
- Department of Optics, Complutense University of Madrid
- Enrique López Cabarcos
- Departamento de Química en Ciencias Farmacéuticas, Universidad Complutense de Madrid
- Nuria Fernández
- Nanobiology Group, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Ramón y Cajal
- Irene Chaves-Coira
- Departament of Anatomy, Histology and Neuroscience, Facultad de Medicina, Universidad Autónoma de Madrid
- Daniel Lucena-Agell
- Chemical and Physical Biology, Centro de Investigaciones Biologicas, Consejo Superior de Investigaciones Cientificas CIB–CSIC
- Luis Monge
- Nanobiology Group, Instituto Ramón y Cajal de Investigación Sanitaria, Hospital Ramón y Cajal
- Mark D. Mackenzie
- Institute of Photonics and Quantum Sciences (IPaQS), School of Engineering and Physical Sciences, Heriot-Watt University
- José Marqués-Hueso
- Institute of Sensors, Signals and Systems (ISSS), School of Engineering & Physical Sciences (EPS), Heriot-Watt University
- Callum M. S. Jones
- Institute of Sensors, Signals and Systems (ISSS), School of Engineering & Physical Sciences (EPS), Heriot-Watt University
- Carlos Jacinto
- Group of Nano-Photonics and Imaging, Instituto de Física, Universidade Federal de Alagoas
- Blanca del Rosal
- Centre for Micro-Photonics, Faculty of Science, Engineering and Technology, Swinburne University of Technology
- Ajoy K. Kar
- Institute of Photonics and Quantum Sciences (IPaQS), School of Engineering and Physical Sciences, Heriot-Watt University
- Jorge Rubio-Retama
- Departamento de Química en Ciencias Farmacéuticas, Universidad Complutense de Madrid
- Daniel Jaque
- Fluorescence Imaging Group, Departamento de Física de Materiales, Facultad de Ciencias, Universidad Autónoma de Madrid
- DOI
- https://doi.org/10.1038/s41467-020-16333-2
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 12
Abstract
Deep tissue imaging has been limited by the low brightness of probes emitting in the second near-infrared window. Here, the authors use femtosecond laser irradiation to grow a protective shell on Ag2S nanoparticles, achieving 80-fold quantum yield enhancement and imaging with low excitation intensities.
