Nature Communications (Mar 2022)

Arabidopsis RBV is a conserved WD40 repeat protein that promotes microRNA biogenesis and ARGONAUTE1 loading

  • Chao Liang,
  • Qiang Cai,
  • Fei Wang,
  • Shaofang Li,
  • Chenjiang You,
  • Chi Xu,
  • Lei Gao,
  • Dechang Cao,
  • Ting Lan,
  • Bailong Zhang,
  • Beixin Mo,
  • Xuemei Chen

DOI
https://doi.org/10.1038/s41467-022-28872-x
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 14

Abstract

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MicroRNAs regulate gene expression through RNA cleavage or translation repression. Here the authors show that RBV, an evolutionarily conserved WD40 domain protein, acts to promote MIR transcription, pri-miRNA processing and miRNA loading into AGO1.