Coronary computed tomographic angiographic imaging of cardiac allograft preserved in Paragonix SherpaPak Cardiac Transport System

Marian Urban, MD, PhD; Brian D. Lowes, MD, PhD; Stanley J. Radio, MD; Ahmad Alshomrani, MBBS; Marshall P. Hyden, MD; Robbie Garvin, MD; Kim F. Duncan, MD; Nicholas W. Markin, MD; John Y. Um, MD; Chad Hovseth, RT; Samer H. Sayyed, MD

JHLT Open (Nov 2024)

Coronary computed tomographic angiographic imaging of cardiac allograft preserved in Paragonix SherpaPak Cardiac Transport System

Marian Urban, MD, PhD,
Brian D. Lowes, MD, PhD,
Stanley J. Radio, MD,
Ahmad Alshomrani, MBBS,
Marshall P. Hyden, MD,
Robbie Garvin, MD,
Kim F. Duncan, MD,
Nicholas W. Markin, MD,
John Y. Um, MD,
Chad Hovseth, RT,
Samer H. Sayyed, MD

Affiliations

Marian Urban, MD, PhD: Department of Surgery, Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, Nebraska; Corresponding author: Marian Urban, MD, PhD, Department of Surgery, Division of Cardiothoracic Surgery, University of Nebraska Medical Center, 42nd and, Emile St, Omaha, NE 68198.
Brian D. Lowes, MD, PhD: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska
Stanley J. Radio, MD: Department of Pathology, Microbiology and Immunology, University of Nebraska Medical Center, Omaha, Nebraska
Ahmad Alshomrani, MBBS: Department of Pathology, Microbiology and Immunology, University of Nebraska Medical Center, Omaha, Nebraska
Marshall P. Hyden, MD: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska
Robbie Garvin, MD: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska
Kim F. Duncan, MD: Department of Surgery, Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, Nebraska
Nicholas W. Markin, MD: Department of Anesthesiology, University of Nebraska Medical Center, Omaha, Nebraska
John Y. Um, MD: Department of Surgery, Division of Cardiothoracic Surgery, University of Nebraska Medical Center, Omaha, Nebraska
Chad Hovseth, RT: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska
Samer H. Sayyed, MD: Department of Internal Medicine, Division of Cardiovascular Medicine, University of Nebraska Medical Center, Omaha, Nebraska

Journal volume & issue: Vol. 6
p. 100142

Abstract

Read online

Donation after circulatory death (DCD) heart transplantation is emerging as an alternative pathway to traditional donation after brain death (DBD) to expand the heart donor pool. Greater adoption of DCD heart allografts is hampered by the logistical and ethical constraints to perform invasive antemortem testing, thus limiting the capacity for the standard donor organ quality evaluation. Identification of the absence of coronary artery disease in patients at risk is an essential prerequisite for organ acceptance by an implant institution. This case presents a novel approach to the examination of coronary arteries in a cardiac allograft. We demonstrated that the coronary computed tomographic angiographic imaging of an ex-situ nonbeating cardiac allograft preserved after recovery in SherpaPak Cardiac Transport System is technically feasible. The images are of good quality and allow for three-dimensional reconstruction as well as quantification of coronary lesions.

Published in JHLT Open

ISSN: 2950-1334 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Surgery; Medicine: Internal medicine: Specialties of internal medicine
Website: https://www.sciencedirect.com/journal/jhlt-open

About the journal

Abstract

Keywords