THE EFFECTIVENESS OF OZONE THERAPY FOR ARTERIAL HYPERTENSION AND CONCOMITANT GASTROPATHY IN MINERS

Abstract

Objective: To evaluate the effectiveness of ozone therapy in the combination of arterial hypertension (AH) and gastropathy in miners. Methods: Two groups of male miners with AH and gastropathy were analyzed: group I – 43 miners aged 47.4±1.3 years with work experience of 27.9±1.9 years and group II – 42 miners aged 46.9±1.4 years with work experience of 27.1±1.8 years. Group II received drug treatment only, and group I, in addition, received ozone therapy. An ozone-oxygen mixture was administered intravenously in an amount of 200-400 ml with an ozone concentration in a solution of 1-1.5 mg/l five times every other day. To assess the effectiveness of the ozone therapy, the lipid profile was studied, the level of blood pressure was monitored, and fibrogastroduodenoscopy was performed. Patients were examined before the start of the course of ozone therapy, control examinations were carried out on the 12th day from the moment of treatment. Results: In both groups, individuals with grade I AH showed a statistically significant (p<0.0001) decrease in both SBP and DBP by the 12th day of hospital stay. Changes in the lipid profile were noted in group I: the concentrations of total cholesterol and triglycerides decreased by 1.3 and 1.4 times, respectively compared to the initial data; the atherogenic index of plasma approached normal values, which was not observed in group II. The condition of the gastroduodenal mucosa in the group I improved: atrophic-sclerotic signs underwent positive changes in 56% of cases; in patients with erosive lesions, mucosal regeneration was noted in all cases. In group II, atrophic processes of the mucosa remained unchanged, while erosive lesions of the mucosa decreased only 1.5-2 times. Conclusion: This study testifies to the effectiveness of ozone therapy in the complex treatment of arterial hypertension in combination with erosive and atrophic lesions of the gastroduodenal zone.

Keywords

• arterial hypertension
• gastroduodenal zone
• erosive gastritis
• ozone therapy
• triglycerides
• total cholesterol