De novo upper tract urothelial carcinoma after renal transplantation: a single-center experience in China

Abstract

Highlights Both higher tumor staging and positive lymph node status were associated with a worse cancer-specific survival in patients with post-transplant de novo UTUC. Aristolochic acid was associated with multifocality of tumors and higher incidence of contralateral upper tract recurrence. Prophylactic contralateral resection was suggested for post-transplant UTUC, especially for patients with aristolochic acid exposure.

Keywords

• Renal transplantation
• Upper tract urothelial carcinoma
• Aristolochic acid
• Prognosis
• Prophylactic contralateral resection