Brine Shrimp test Triterpenes from root bark of Sandoricum emarginatum

Abstract

The root of Sondoricum emargiatum , Meliaceae was collected in North Tapanuli, North Sumatera. Local people use this timber plany for construction and the fruit bark for cooking (Naito, 1986). In the previous investigation, 1,3,4 cuparatrien-15-ol, 4.15-cubebene and secobryononic acid were isolated from stem bark of Sondoricum emargiatum (Pratiwi). Further fractionation of n-hexane extract of root bark of Sondoricum emargiatum in the isolation of two triterpenes resulted byononic (1) and 3,4-seco-olean-4 (23), 12-dien-3,29-dionic acids (3) and their structures were elucidated by IR, MS, and NMR-spectroscopy. Compound (1) and (3) were forund more active than methyl bryononic derivate (2) with Brine Shrimp as bioindicator.

Keywords

• Brine shrimp test