Targeting BUB3 in combination with paclitaxel inhibits proliferation of glioblastoma cells by enhancing cellular senescence

• Patrícia M. A. Silva,
• Ana V. Nascimento,
• Olga Martinho,
• Rui M. Reis,
• Hassan Bousbaa

Affiliations

Patrícia M. A. Silva

UNIPRO - Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal; TOXRUN - Toxicology Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal.

Ana V. Nascimento

UNIPRO - Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal.

Olga Martinho

Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo 14784-400, Brazil.

Rui M. Reis

Life and Health Sciences Research Institute (ICVS), Medical School, University of Minho, Campus de Gualtar, 4710-057 Braga, Portugal; Molecular Oncology Research Center, Barretos Cancer Hospital, São Paulo 14784-400, Brazil.

Hassan Bousbaa

UNIPRO - Oral Pathology and Rehabilitation Research Unit, University Institute of Health Sciences (IUCS), CESPU, Rua Central de Gandra, 1317, 4585-116 Gandra, Portugal; Interdisciplinary Center of Marine and Environmental Research (CIIMAR), University of Porto, Terminal de Cruzeiros do Porto de Leixões, Av. General Norton de Matos s/n 4450-208 Matosinhos, Portugal.