Characteristics of patients with blastemal-type Wilms’ tumour

Abstract

Wilms’ tumour (nephroblastoma) is the most common malignant tumour of kidney in children and one of the 2 most common solid tumours located outside of the central nervous system. Nephroblastoma has a very good prognosis, but some histological types like blastemal-type require qualification to a high-risk group and intensification of treatment. We present the cases of 3 children diagnosed with nephroblastoma, blastemal-type. The first girl’s treatment was unsuccessful, as there were 4 cancer recurrences. The second girl had primarily metachronous form of nephroblastoma, but during recurrence the blastemal-type was diagnosed. Despite intensive treatment, it ended with failure. The third girl had a tumour in the left kidney, which was transformed from the bilateral nephroblastomatosis. She remains in remission; the therapy ended on February 2018.

Keywords

• wilms’ tumor
• nephroblastoma
• blastemal-type.