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Frontiers in Immunology
(Nov 2021)
CAR T-Cell Therapy: Is CD28-CAR Heterodimerization Its Achilles’ Heel?
Leonardo M. R. Ferreira,
Leonardo M. R. Ferreira,
Yannick D. Muller
Affiliations
Leonardo M. R. Ferreira
Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, United States
Leonardo M. R. Ferreira
Hollings Cancer Center, Medical University of South Carolina, Charleston, SC, United States
Yannick D. Muller
Division of Immunology and Allergy, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
DOI
https://doi.org/10.3389/fimmu.2021.766220
Journal volume & issue
Vol. 12
Abstract
Read online
No abstracts available.
Keywords
chimeric antigen receptor
CD28
CD19 CAR T-cell
transmembrane domain
heterodimerization
cytokine release syndrome
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