Evaluation of Biological-rhythm Using the Biological Rhythm Interview of Assessment in Neuropsychiatry (BRIAN) in Rheumatoid Arthritis

Abstract

Aim:We aimed to evaluate biological rhythm in rheumatoid arthritis (RA) patients using the Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN).Methods:Eighty-five RA patients and 85 healthy controls were included in the study. Biological rhythm was evaluated using the BRIAN. Disease activity was determined by the Disease Activity Score in 28 joints in RA patients.Results:The BRIAN total score and sleep, activity, social rhythm and eating pattern scores were higher in patients with RA than in controls (BRIAN scale total score-44.8±8.6 vs 25.76±5.86 (p<0.001), sleep score 14.2±3.0 vs 8.32±1.48 (p<0.001), activity score 14.67±2.38 vs 6.21±2.92 (p<0.001), social score 8.68±1.33 vs 6.64±1.48 (p<0.001) and eating score 9.65±2.75 vs 5.83±1.11 (p<0.001). A positive correlation was found between the Disease Activity Score-28 and BRIAN total score (p=0.041, r=0.224).Conclusion:RA may affect sleep patterns, activities of daily living and eating habits. RA patients should be evaluated in this respect and evaluation of patients with RA should include the circadian rhythm.

Keywords

• rheumatoid arthritis
• biological rhythm
• biological rhythms interview for assessment in neuropsychiatry scale