Loss of zinc transporters ZIP1 and ZIP3 augments platelet reactivity in response to thrombin and accelerates thrombus formation in vivo

• Amro Elgheznawy,
• Patricia Öftering,
• Maximilian Englert,
• Kristina Mott,
• Friederike Kaiser,
• Charly Kusch,
• Uwe Gbureck,
• Michael R. Bösl,
• Harald Schulze,
• Bernhard Nieswandt,
• Timo Vögtle,
• Heike M. Hermanns

Affiliations

Amro Elgheznawy

Medical Clinic II, Division of Hepatology, University Hospital Würzburg, Würzburg, Germany

Patricia Öftering

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Maximilian Englert

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Kristina Mott

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Friederike Kaiser

Department for Functional Materials in Medicine and Dentistry, University Hospital Würzburg, Würzburg, Germany

Charly Kusch

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Uwe Gbureck

Department for Functional Materials in Medicine and Dentistry, University Hospital Würzburg, Würzburg, Germany

Michael R. Bösl

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Harald Schulze

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Bernhard Nieswandt

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Timo Vögtle

Institute of Experimental Biomedicine I, University Hospital Würzburg and Rudolf Virchow Center for Integrative and Translational Bioimaging, University of Würzburg, Würzburg, Germany

Heike M. Hermanns

Medical Clinic II, Division of Hepatology, University Hospital Würzburg, Würzburg, Germany