Case report: Large follicular thyroid carcinoma with multiple cervical lymph node metastases

Fei Ye; Liyan Liao; Wanlin Tan; Wanlin Tan; Yi Gong; Xiaodu Li; Xiaodu Li; Chengcheng Niu; Chengcheng Niu

doi:10.3389/fsurg.2022.995859

Frontiers in Surgery (Aug 2022)

Case report: Large follicular thyroid carcinoma with multiple cervical lymph node metastases

Fei Ye,
Liyan Liao,
Wanlin Tan,
Wanlin Tan,
Yi Gong,
Xiaodu Li,
Xiaodu Li,
Chengcheng Niu,
Chengcheng Niu

Affiliations

Fei Ye: Department of Thyroid Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Liyan Liao: Department of Pathology, The Second Xiangya Hospital, Central South University, Changsha, China
Wanlin Tan: Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China
Wanlin Tan: Research Center of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, China
Yi Gong: Department of Thyroid Surgery, The Second Xiangya Hospital, Central South University, Changsha, China
Xiaodu Li: Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China
Xiaodu Li: Research Center of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, China
Chengcheng Niu: Department of Ultrasound Diagnosis, The Second Xiangya Hospital, Central South University, Changsha, China
Chengcheng Niu: Research Center of Ultrasonography, The Second Xiangya Hospital, Central South University, Changsha, China

DOI: https://doi.org/10.3389/fsurg.2022.995859
Journal volume & issue: Vol. 9

Abstract

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IntroductionFollicular thyroid carcinoma (FTC) rarely metastasizes to regional lymph nodes, as they mainly metastasize through hematogenous route; in particular, a large FTC with only lateral lymph node metastasis and without distant metastasis has rarely been reported.Case reportWe present a 66-year-old male patient with a progressively growing thyroid for more than 20 years, causing tracheal compression and narrowing. Neck ultrasonography, computed tomography (CT), magnetic resonance (MR) imaging and positron emission tomography–computed tomography (PET/CT) were carried out to obtain images of the thyroid and surrounding tissues. Total thyroidectomy and cervical lateral and central lymph node dissection were undertaken, and histopathological, and immunohistochemical evaluations and molecular pathology confirmed the diagnosis of FTC with multiple cervical lymph node metastases.ConclusionWe have reported a rare case of large FTC with diffuse nodal involvement but no distant metastases. We present the thyroid ultrasound, neck CT, MR and whole body PET/CT.

Published in Frontiers in Surgery

ISSN: 2296-875X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Surgery
Website: https://www.frontiersin.org/journals/surgery

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