Pharmaceutics (Feb 2023)

Advances in Self-Assembled Peptides as Drug Carriers

  • Yawen Gao,
  • Lele Wang,
  • Xue Zhang,
  • Ziling Zhou,
  • Xinzhu Shen,
  • Haodong Hu,
  • Rui Sun,
  • Jihui Tang

DOI
https://doi.org/10.3390/pharmaceutics15020482
Journal volume & issue
Vol. 15, no. 2
p. 482

Abstract

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In recent years, self-assembled peptide nanotechnology has attracted a great deal of attention for its ability to form various regular and ordered structures with diverse and practical functions. Self-assembled peptides can exist in different environments and are a kind of medical bio-regenerative material with unique structures. These materials have good biocompatibility and controllability and can form nanoparticles, nanofibers and hydrogels to perform specific morphological functions, which are widely used in biomedical and material science fields. In this paper, the properties of self-assembled peptides, their influencing factors and the nanostructures that they form are reviewed, and the applications of self-assembled peptides as drug carriers are highlighted. Finally, the prospects and challenges for developing self-assembled peptide nanomaterials are briefly discussed.

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