South African Journal of Radiology (Oct 2024)

Advanced tumour-induced osteomalacia secondary to sinonasal phosphaturic mesenchymal tumour

  • Monica van Wijk,
  • Leon Janse van Rensburg,
  • Bianca D. Berndorfler,
  • Johan F. Opperman,
  • Johan Grobbelaar,
  • Amir H. Afrogheh,
  • Sarah Versveld,
  • Razaan Davis

DOI
https://doi.org/10.4102/sajr.v28i1.2975
Journal volume & issue
Vol. 28, no. 1
pp. e1 – e6

Abstract

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Phosphaturic mesenchymal tumours (PMT) are rare, benign lesions and the most common tumour to cause tumour-induced osteomalacia (TIO), a paraneoplastic syndrome. Patients frequently exhibit severe osteomalacia, accompanied by multiple fractures, which significantly impair their quality of life. Complete surgical resection is curative. Contribution: A rare case of sinonasal PMT is presented, with a focus on the imaging findings and role of the radiologist and nuclear physician.

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