Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing

Shengqiang Chen; Yanxia Zhu; Qingqing Xu; Qi Jiang; Danyang Chen; Ting Chen; Xishen Xu; Zhaokui Jin; Qianjun He

doi:10.1038/s41467-022-33475-7

Nature Communications (Sep 2022)

Photocatalytic glucose depletion and hydrogen generation for diabetic wound healing

Shengqiang Chen,
Yanxia Zhu,
Qingqing Xu,
Qi Jiang,
Danyang Chen,
Ting Chen,
Xishen Xu,
Zhaokui Jin,
Qianjun He

Affiliations

Shengqiang Chen: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University
Yanxia Zhu: Department of Cell Biology and Medical Genetics, School of Basic Medical Sciences, Shenzhen University Health Science Center
Qingqing Xu: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University
Qi Jiang: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University
Danyang Chen: Shanghai Key Laboratory of Hydrogen Science & Shanghai Key Laboratory of Hydrogen Science & Center of Hydrogen Science, School of Materials Science and Engineering, Shanghai Jiao Tong University
Ting Chen: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University
Xishen Xu: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University
Zhaokui Jin: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University
Qianjun He: Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, School of Biomedical Engineering, Health Science Center, Shenzhen University

DOI: https://doi.org/10.1038/s41467-022-33475-7
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 11

Abstract

Read online

Hydrogenation is a treatment for chronic inflammation caused by high glucose levels in diabetic ulcers, However, current therapies have limitations. Here, the authors report on the creation of a visible light photocatalytic agent which depletes glucose in the wound and generates hydrogen to aid in diabetic wound healing.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal