Nature Communications (May 2020)

Size and surface charge characterization of nanoparticles with a salt gradient

  • Martin K. Rasmussen,
  • Jonas N. Pedersen,
  • Rodolphe Marie

DOI
https://doi.org/10.1038/s41467-020-15889-3
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 8

Abstract

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Exosomes are used as disease biomarkers, but their characterization in biological samples is challenging. Here the authors achieve simultaneous characterization of size and zeta potential of individual nanoparticles and particle mixtures at physiological salinity conditions, exploiting a salt gradient in a capillary channel.