Closed-loop direct control of seizure focus in a rodent model of temporal lobe epilepsy via localized electric fields applied sequentially

Wonok Kang; Chanyang Ju; Jaesoon Joo; Jiho Lee; Young-Min Shon; Sung-Min Park

doi:10.1038/s41467-022-35540-7

Nature Communications (Dec 2022)

Closed-loop direct control of seizure focus in a rodent model of temporal lobe epilepsy via localized electric fields applied sequentially

Wonok Kang,
Chanyang Ju,
Jaesoon Joo,
Jiho Lee,
Young-Min Shon,
Sung-Min Park

Affiliations

Wonok Kang: School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology
Chanyang Ju: Medical Device Innovation Center, Pohang University of Science and Technology
Jaesoon Joo: Biomedical Engineering Research Center, Samsung Medical Center, School of Medicine, Sungkyunkwan University
Jiho Lee: Medical Device Innovation Center, Pohang University of Science and Technology
Young-Min Shon: Biomedical Engineering Research Center, Samsung Medical Center, School of Medicine, Sungkyunkwan University
Sung-Min Park: School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology

DOI: https://doi.org/10.1038/s41467-022-35540-7
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 18

Abstract

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Direct stimulation of the focus of a seizure may have potential for the treatment of epilepsy. Here the authors demonstrate in a rat model a sequential narrow-field stimulation method for terminating seizures.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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